If other tests are inconclusive, your doctor may recommend a procedure to remove a sample of tissue from your liver (liver biopsy). The tissue sample is examined in a laboratory to look for signs of inflammation and scarring. A liver biopsy may be painful in some patients, and it does have small risks that your doctor will review with you in detail. This procedure is performed by a needle insertion through the abdominal wall and into the liver.
The first line of treatment is usually weight loss through a combination of a healthy diet and exercise. Losing weight addresses the conditions that contribute to nonalcoholic fatty liver disease. Ideally, a loss of 10 percent of body weight is desirable, but improvement in risk factors can become apparent if you lose even three to five percent of your starting weight. Weight-loss surgery is also an option for those who need to lose a great deal of weight.
Your doctor may recommend that you receive vaccinations against hepatitis A and hepatitis B to help protect you from viruses that may cause further liver damage.
For those who have cirrhosis due to nonalcoholic steatohepatitis, liver transplantation may be an option. Outcomes of liver transplant in this population group are generally very good.